★★★★⯨ 4.6 - Rated 4.6 out of 5 stars • Based on 550 reviews
*Rating and review count are based on customer reviews published on the manufacturer's website.*

( plated )™ Skin Science INTENSE Serum delivers the same award-winning regenerative skincare formula found in the original INTENSE Serum, now in a convenient refill cartridge designed exclusively for the reusable INTENSE Serum bottle. Powered by proprietary Renewosome™ Technology, this advanced serum harnesses the regenerative potential of platelet-derived exosomes to help visibly improve the appearance of fine lines, wrinkles, uneven skin tone, redness, texture, and overall skin quality while supporting the skin's natural renewal process.

Unlike traditional anti-aging serums that primarily focus on hydration or exfoliation, INTENSE Serum works by supporting cellular communication through platelet-derived exosomes—naturally occurring extracellular vesicles that help encourage healthier-looking, more resilient skin. Combined with low molecular weight hyaluronic acid and a proprietary antioxidant complex, the lightweight formula delivers comprehensive support for smoother, firmer, brighter, and more youthful-looking skin with continued daily use.

Designed with sustainability in mind, the refill cartridge allows you to continue your skincare regimen while reducing packaging waste. Simply replace the empty cartridge in your reusable INTENSE Serum bottle and enjoy the same physician-developed formula trusted by dermatologists, plastic surgeons, and skincare professionals.

Awards & Recognition

🏆 TIME Best Inventions 2024

🏆 Oprah Daily Editor's Choice 2024

🏆 Oprah Daily Editor's Choice 2023

🏆 NewBeauty Award Winner 2025

🏆 NewBeauty Award Winner 2024

🏆 GQ Grooming Award 2025

🏆 Cosmopolitan Holy Grail Beauty Award 2025

🏆 Marie Claire Hair & Skin Award 2025 – Best Serum for Mature Skin

Key Benefits

✔️ Helps reduce the appearance of fine lines and wrinkles

✔️ Supports firmer, smoother, more youthful-looking skin

✔️ Helps improve uneven skin tone and texture

✔️ Helps minimize the appearance of redness

✔️ Supports the skin's natural renewal process

✔️ Delivers lightweight hydration without feeling heavy

✔️ Helps defend against environmental oxidative stress

✔️ Powered by proprietary Renewosome™ Technology

✔️ Sustainable refill system reduces packaging waste

✔️ Suitable for all skin types

Key Ingredients

Proprietary Renewosome™ Technology

Renewosome™ Technology features platelet-derived exosomes designed to support the skin's natural regenerative processes through advanced cellular communication.

Benefits:

✔️ Supports healthier-looking skin

✔️ Helps improve visible firmness

✔️ Promotes smoother skin texture

✔️ Helps reduce the appearance of fine lines and wrinkles

Platelet-Derived Exosomes

Naturally occurring extracellular vesicles that help support skin renewal by promoting healthy cellular signaling.

Benefits:

✔️ Supports skin regeneration

✔️ Helps improve overall skin quality

✔️ Promotes a more youthful appearance

✔️ Supports healthy-looking skin over time

Low Molecular Weight Hyaluronic Acid

Provides deep hydration while helping maintain the skin's moisture barrier.

Benefits:

✔️ Delivers long-lasting hydration

✔️ Helps smooth the appearance of fine lines

✔️ Supports plumper-looking skin

✔️ Enhances overall skin comfort

Proprietary Antioxidant Complex

A carefully selected blend of antioxidants that helps protect the skin from environmental stressors.

Benefits:

✔️ Helps combat free radical damage

✔️ Supports healthier-looking skin

✔️ Promotes long-term skin vitality

✔️ Complements daily skin protection

How to Use

Cleanse and thoroughly dry the skin.

If a refill - Insert the refill cartridge into your reusable ( plated )™ Skin Science INTENSE Serum bottle according to the manufacturer's instructions.

Apply 1–2 pumps evenly over the face, neck, and décolleté.

Allow the serum to absorb for approximately five minutes before applying additional serums, moisturizers, or sunscreen.

Use once or twice daily for optimal results.

Where It Fits in Your Routine

INTENSE Serum should be the first treatment product applied after cleansing.

Morning

1. Cleanser
2. ( plated )™ INTENSE Serum
3. Additional treatment serums (after allowing serum to absorb)
4. Moisturizer
5. Broad-spectrum sunscreen

Evening

1. Cleanser
2. **( plated )™ INTENSE Serum
3. Moisturizer
4. Additional evening treatments if desired

Applying INTENSE Serum immediately after cleansing allows the exosome technology to interact directly with clean skin before layering additional skincare products.

Ideal For

Fine lines and wrinkles

Loss of firmness and elasticity

Uneven skin tone

Rough skin texture

Visible redness

Dull, aging skin

Post-procedure skincare (when recommended by your provider)

Daily regenerative skincare routines

All skin types

Professional Insight

Skin naturally loses its ability to efficiently repair and renew itself over time. As cellular communication slows with age and environmental exposure, visible signs such as fine lines, wrinkles, uneven texture, discoloration, and loss of firmness become more apparent. Rather than relying solely on exfoliation or temporary hydration, regenerative skincare focuses on supporting the skin's own natural renewal processes.

( plated )™ Skin Science INTENSE Serum utilizes proprietary Renewosome™ Technology featuring platelet-derived exosomes to help support healthy cellular communication within the skin. These microscopic extracellular vesicles help encourage the skin's natural regenerative response, promoting smoother texture, improved firmness, and a healthier-looking complexion over time. Combined with hydrating hyaluronic acid and antioxidant protection, the formula addresses multiple visible signs of aging while maintaining a lightweight, elegant feel suitable for daily use.

The refill cartridge provides the same physician-developed, award-winning formula as the original serum while offering a more sustainable option for maintaining your skincare routine. Consistent daily use helps maximize the cumulative benefits of regenerative skincare while reducing unnecessary packaging waste.

Professional Recommendation

( plated )™ Skin Science INTENSE Serum is especially beneficial for:

✔️ Fine lines and wrinkles

✔️ Mature skin

✔️ Loss of firmness

✔️ Uneven texture

✔️ Uneven skin tone

✔️ Visible redness

✔️ Daily regenerative skincare

✔️ Existing INTENSE Serum users

✔️ Individuals seeking advanced exosome technology

What's Included

✔️ 15 mL / 0.5 fl oz of award-winning INTENSE Serum

If a refill - ✔️ One INTENSE Serum Refill Cartridge

Please Note: This refill cartridge is compatible only with the reusable ( plated )™ Skin Science INTENSE Serum bottle and is not intended for standalone use.

Formulation Highlights

✔️ Proprietary Renewosome™ Technology

✔️ Platelet-Derived Exosomes

✔️ Low Molecular Weight Hyaluronic Acid

✔️ Proprietary Antioxidant Complex

✔️ Physician-Developed Formula

✔️ Fragrance-Free

✔️ Lightweight, Fast-Absorbing Texture

✔️ Refillable, Sustainable Packaging

✔️ Professional-Grade Regenerative Skincare

✔️ Award-Winning Formula

With consistent use, ( plated )™ Skin Science INTENSE Serum helps visibly improve the appearance of aging skin by supporting the skin's natural regenerative processes through proprietary Renewosome™ Technology. Backed by multiple industry awards and trusted by skincare professionals, this advanced refill system delivers the same breakthrough exosome-powered formula in a more sustainable format, helping you achieve smoother, firmer, healthier-looking skin while reducing environmental impact.