✨ JUST ARRIVED — NEW FROM HYDRINITY

Meet one of the newest innovations from Hydrinity Skin Science: CÉLTHERA™ Advanced Overnight Repair Cream, a clinically advanced overnight treatment that goes far beyond traditional moisturizing. Designed as a 360° cellular repair system, CÉLTHERA™ works while you sleep to support the biological processes associated with healthier, stronger, more youthful-looking skin.

At the center of this new formula is a sophisticated combination of ExoEGF™ Technology, Centella Secretome Concentrate, NAD+ Boost Technology, a Senolytic Renewal Complex, Multi-Ceramide Barrier Blend, Supercharged HA™, and Ectoin. Together, these technologies target multiple factors associated with visible skin aging—including declining cellular energy, compromised barrier function, dehydration, loss of firmness and elasticity, uneven texture, fine lines, wrinkles, and reduced skin resilience.

Unlike a conventional night cream that primarily replaces moisture, CÉLTHERA™ combines regenerative skin science + cellular longevity support + advanced barrier repair. Biomimetic exosome-delivered peptides signal renewal, NAD+ Boost Technology helps support cellular energy, senolytic technology targets aging “zombie” cells, and a multi-ceramide system replenishes essential lipids to reinforce the skin barrier.

The result is a luxurious but highly advanced overnight treatment designed to help skin look firmer, smoother, more hydrated, more resilient, and visibly renewed by morning and over time.

Suitable for all skin types, including sensitive, dry, and aged skin.

---

Key Benefits

✔️ Brand-New Hydrinity Innovation

✔️ Provides 360° overnight cellular repair support

✔️ Helps visibly improve fine lines and wrinkles

✔️ Supports firmer, more elastic-looking skin

✔️ Helps improve uneven skin texture

✔️ Promotes smoother, softer-looking skin

✔️ Provides intensive overnight hydration

✔️ Helps strengthen a compromised skin barrier

✔️ Supports the skin's natural repair processes

✔️ Helps replenish age-related lipid loss

✔️ Supports healthier cellular energy

✔️ Helps target aging “zombie” cells

✔️ Supports collagen and elastin

✔️ Helps improve dull, tired-looking skin

✔️ Promotes youthful-looking radiance

✔️ Helps improve overall skin resilience

✔️ Features biomimetic exosome-delivered peptide technology

✔️ Features NAD+ Boost Technology

✔️ Includes a Multi-Ceramide Barrier Blend

✔️ Clinically tested

✔️ Dermatologist approved

✔️ Suitable for all skin types, including sensitive skin

---

Real Skin. Real Results.

Hydrinity reports noticeable improvements in as little as two weeks with CÉLTHERA™.

212% Improvement in Overall Hydration

CÉLTHERA™ delivered a dramatic improvement in overall skin hydration.

100% Visible Improvement in Overall Skin Appearance

Participants demonstrated visible improvement in overall skin appearance.

78% Softer Skin

Participants experienced noticeably softer-feeling skin.

Hydrinity also reports visible improvement in overall skin appearance and hydration within three weeks, as well as improvement in firmness, smoothness, fine lines, and wrinkles in as little as two weeks.

The manufacturer cites a multi-center, randomized clinical study involving 60 women ages 25–65 across all skin types and conditions, with evaluations conducted throughout a 12-week period.

---

Key Ingredients & Technologies

ExoEGF™ Technology

Biomimetic Exosome-Delivered Vegan Epidermal Growth Factor

ExoEGF™ Technology is one of the most exciting technologies behind CÉLTHERA™.

Hydrinity utilizes a stabilized, biomimetic exosome-delivered Oligopeptide-1, a vegan Epidermal Growth Factor (EGF), designed to support the skin's natural renewal processes. The technology features a sustained 24-hour release system designed to align with the skin's overnight repair cycle.

Hydrinity specifically highlights ExoEGF™ for supporting collagen, elastin, firmness, smoothness, and visible skin renewal.

Benefits:

✔️ Supports the skin's natural renewal processes

✔️ Helps support collagen

✔️ Helps support elastin

✔️ Promotes firmer-looking skin

✔️ Helps improve visible smoothness

✔️ Supports overnight repair

✔️ Provides sustained peptide delivery

✔️ Helps improve overall skin quality

---

Centella Secretome Concentrate

Advanced Signaling Peptide Technology

Centella Secretome Concentrate provides another regenerative component within CÉLTHERA™.

Hydrinity describes this technology as a blend of naturally derived signaling peptides designed to target biological aging while supporting the skin's natural repair processes.

Benefits:

✔️ Supports natural repair processes

✔️ Helps strengthen skin

✔️ Supports visible firmness

✔️ Promotes healthier-looking renewal

✔️ Helps improve skin resilience

✔️ Complements ExoEGF™ Technology

---

NAD+ Boost Technology

Sunflower Seed Sprout Extract

One of the most interesting additions to CÉLTHERA™ is its NAD+ Boost Technology.

NAD+—nicotinamide adenine dinucleotide—is involved in cellular energy production and repair. Hydrinity notes that NAD+ levels naturally decline as skin ages, which can affect visible vitality and resilience.

CÉLTHERA™ uses Sunflower Seed Sprout Extract to help support the skin's natural NAD+ production pathways.

Benefits:

✔️ Supports cellular energy

✔️ Helps promote skin vitality

✔️ Supports natural repair processes

✔️ Helps improve skin resilience

✔️ Supports healthier-looking cellular function

✔️ Promotes a more energized, youthful-looking complexion

---

Senolytic Renewal Complex

Targeting Aging “Zombie” Cells

The Senolytic Renewal Complex brings an especially innovative longevity-focused component to CÉLTHERA™.

As cells age, some can enter a state known as cellular senescence. These cells are often informally referred to as “zombie cells” because they stop dividing but remain biologically active.

Hydrinity describes CÉLTHERA's Senolytic Renewal Complex as helping target these aging cells to promote healthier cellular function.

Benefits:

✔️ Targets visible factors associated with biological aging

✔️ Supports healthier cellular function

✔️ Promotes skin renewal

✔️ Helps improve overall skin vitality

✔️ Supports a healthier-looking complexion over time

---

Multi-Ceramide Barrier Blend

A sophisticated regenerative treatment still needs a healthy skin barrier.

CÉLTHERA™ contains multiple ceramides, including Ceramide NP, Ceramide NS, Ceramide EOP, and Ceramide AP, together with cholesterol and other skin-conditioning lipids.

Hydrinity designed this complex to replenish skin lipids, strengthen the moisture barrier, and help reduce age-related moisture loss.

Benefits:

✔️ Replenishes essential skin lipids

✔️ Helps strengthen the moisture barrier

✔️ Helps reduce moisture loss

✔️ Supports dry and compromised skin

✔️ Improves skin comfort

✔️ Helps increase resilience

✔️ Supports softer, smoother-looking skin

---

Supercharged HA™

Advanced Hyaluronic Acid Hydration

CÉLTHERA™ incorporates Hydrinity's advanced Hyaluronic Acid technology to provide intensive moisture support while the skin undergoes its overnight renewal process.

Hyaluronic Acid helps attract and retain water, supporting the plump, supple appearance associated with healthy skin.

Benefits:

✔️ Provides intensive hydration

✔️ Helps plump dehydration lines

✔️ Supports smoother-looking skin

✔️ Helps improve visible suppleness

✔️ Supports moisture retention

✔️ Complements barrier-repair ingredients

---

Ectoin

Hydroprotective + Stress-Defense Molecule

Ectoin is a powerful hydroprotective molecule incorporated to help improve the skin's ability to retain water while protecting against environmental and cellular stress.

Hydrinity specifically highlights Ectoin for helping improve water-retention capacity and enhancing visible skin smoothness.

Benefits:

✔️ Helps improve water retention

✔️ Supports skin hydration

✔️ Helps protect stressed skin

✔️ Supports barrier resilience

✔️ Helps improve visible smoothness

✔️ Supports sensitive skin

---

Niacinamide

Vitamin B3

CÉLTHERA™ also contains Niacinamide, one of the most versatile ingredients for supporting healthy barrier function, more even-looking tone, visible pore refinement, and overall skin resilience.

Benefits:

✔️ Supports barrier function

✔️ Helps improve visible texture

✔️ Supports more even-looking tone

✔️ Helps improve overall skin quality

✔️ Supports skin resilience

---

Squalane

Squalane provides lightweight lipid replenishment and helps soften and condition the skin without creating an excessively heavy feel.

Benefits:

✔️ Helps replenish moisture

✔️ Supports barrier health

✔️ Improves skin softness

✔️ Helps reduce dryness

✔️ Supports smoother-looking skin

---

Urea

Urea is a naturally occurring component of the skin's Natural Moisturizing Factor and provides valuable humectant and conditioning benefits.

Benefits:

✔️ Helps increase hydration

✔️ Supports softer skin

✔️ Helps improve rough texture

✔️ Supports barrier comfort

---

How to Use

Use CÉLTHERA™ Advanced Overnight Repair Cream in the evening.

After cleansing and applying your appropriate treatment products, dispense 1–2 pumps.

Smooth evenly over the face, neck, and décolleté.

Massage gently until fully absorbed.

Hydrinity recommends cleansing with PRELUDE Facial Treatment Cleanser before application.

CÉLTHERA™ can also complement a nighttime routine containing retinol or retinal products. Hydrinity recommends introducing retinoids gradually and adjusting frequency according to individual skin tolerance.

---

Where It Fits in Your Routine

CÉLTHERA™ is designed to function as the repairing and moisturizing step of your evening routine.

Evening

1. Cleanser
2. Treatment Serum
3. Corrective Treatment
4. Retinal/Retinoid Treatment, when appropriate
5. Hydrinity® CÉLTHERA™ Advanced Overnight Repair Cream

For an advanced Hydrinity renewal routine, CÉLTHERA™ can be paired with RetaXome™ Retinal Boost Treatment Pads every third night, while CÉLTHERA™ is used nightly. This combination was specifically evaluated in Hydrinity's clinical testing.

---

Ideal For

Fine lines and wrinkles

Loss of firmness

Loss of elasticity

Uneven skin texture

Dull or tired-looking skin

Dryness and dehydration

Compromised skin barrier

Loss of youthful radiance

Reduced skin resilience

Mature or aged skin

Sensitive skin

Clients seeking regenerative skincare

Clients interested in skin longevity

Individuals seeking advanced overnight repair

Clients using retinal or retinoid products

Individuals wanting more than a traditional moisturizer

Hydrinity specifically states that CÉLTHERA™ is suitable for all skin types and particularly appropriate for individuals experiencing fine lines, wrinkles, loss of firmness, uneven texture, dullness, and decreased skin resilience.

---

Professional Insight

CÉLTHERA™ is one of the most exciting new Hydrinity arrivals because calling it simply a “night cream” doesn't really explain what this product is designed to do.

A traditional night cream typically focuses on one primary objective:

Moisture.

CÉLTHERA™ starts there—but then goes considerably further.

Hydrinity designed this as a 360° cellular repair system that addresses several interconnected factors associated with how skin visibly ages: cellular signaling, declining cellular energy, senescent cells, collagen and elastin support, lipid depletion, barrier deterioration, and moisture loss.

That creates a very different strategy from simply putting a richer moisturizer on at night.

---

Why Overnight Repair Matters

Nighttime is an ideal opportunity to give the skin an intensive combination of regenerative and barrier-supporting ingredients.

CÉLTHERA™ takes advantage of that window with its 24-hour sustained-release ExoEGF™ Technology, designed to support the skin's natural renewal processes while promoting the appearance of collagen, elastin, firmness, and smoothness.

At the same time, NAD+ Boost Technology supports cellular energy, the Senolytic Renewal Complex targets aging cellular behavior, and the Multi-Ceramide Barrier Blend helps rebuild the lipid environment necessary for healthy barrier function.

So rather than focusing on a single pathway, CÉLTHERA™ approaches overnight skin renewal from several directions simultaneously:

Repair.

Regenerate.

Energize.

Restore.

Replenish.

Protect.

That is the real story behind this formula.

---

Exosomes + NAD+ + Senolytic Technology

This combination is what makes CÉLTHERA™ particularly different from many traditional moisturizers.

ExoEGF™ Technology — Repair

Biomimetic exosome-delivered vegan Epidermal Growth Factor helps signal renewal while supporting collagen, elastin, firmness, and smoothness.

Centella Secretome Concentrate — Strengthen + Firm

Naturally derived signaling peptides support the skin's natural repair mechanisms.

NAD+ Boost Technology — Energize

Sunflower Seed Sprout Extract helps support pathways associated with the skin's natural NAD+ production and cellular energy.

Senolytic Renewal Complex — Restore

Targets aging “zombie” cells to support healthier cellular function.

Multi-Ceramide Barrier Blend — Replenish

Replenishes essential lipids to strengthen the barrier and help reduce age-related moisture loss.

Ectoin — Protect

Helps increase the skin's water-retention capacity while supporting protection against stress.

This is an unusually comprehensive approach for a single overnight moisturizer.

---

CÉLTHERA™ + RetaXome™: An Advanced Nighttime Pairing

For clients looking for an even more advanced Hydrinity regimen, CÉLTHERA™ pairs especially well with the new RetaXome™ Retinal Boost Treatment Pads.

The RetaXome™ pads provide retinal renewal and multi-acid resurfacing every third night, while CÉLTHERA™ provides nightly regenerative, hydrating, and barrier-supportive care.

Hydrinity actually evaluated this combination clinically. Participants used PRELUDE Facial Treatment Cleanser, RetaXome™ Retinal Boost Treatment Pads every third night, and CÉLTHERA™ nightly, with visible improvements in firmness, smoothness, fine lines, and wrinkles reported in as little as two weeks.

That pairing makes a lot of sense:

RetaXome™ helps renew and resurface.

CÉLTHERA™ helps repair, replenish, strengthen, and hydrate.

For someone looking to build an advanced nighttime skin-renewal regimen, these two new Hydrinity products were clearly designed to complement one another.

---

Professional Recommendation

Hydrinity® CÉLTHERA™ Advanced Overnight Repair Cream is especially beneficial for:

✔️ Fine lines and wrinkles

✔️ Loss of firmness and elasticity

✔️ Dry or dehydrated skin

✔️ Compromised skin barrier

✔️ Dull, tired-looking skin

✔️ Uneven skin texture

✔️ Loss of radiance

✔️ Mature skin

✔️ Sensitive skin

✔️ Environmentally stressed skin

✔️ Clients seeking advanced regenerative skincare

✔️ Clients focused on skin longevity

✔️ Individuals using retinal or retinoid treatments

✔️ Clients wanting advanced barrier repair

✔️ Individuals wanting more than a traditional night cream

✔️ Clients looking to pair CÉLTHERA™ with RetaXome™ Retinal Boost Treatment Pads

---

Formulation Highlights

✔️ NEW ARRIVAL

✔️ 360° Cellular Repair System

✔️ ExoEGF™ Technology

✔️ Biomimetic Exosome-Delivered Oligopeptide-1

✔️ Vegan Epidermal Growth Factor Technology

✔️ 24-Hour Sustained-Release Peptide Technology

✔️ Centella Secretome Concentrate

✔️ NAD+ Boost Technology

✔️ Sunflower Seed Sprout Extract

✔️ Senolytic Renewal Complex

✔️ Multi-Ceramide Barrier Blend

✔️ Ceramide NP

✔️ Ceramide NS

✔️ Ceramide EOP

✔️ Ceramide AP

✔️ Cholesterol

✔️ Phosphatidylcholine

✔️ Supercharged HA™

✔️ Hyaluronic Acid

✔️ Ectoin

✔️ Niacinamide

✔️ Squalane

✔️ Urea

✔️ Centella Asiatica Leaf Extract

✔️ Kakadu Plum Extract

✔️ Apple Fruit Cell Culture Extract

✔️ Grape Fruit Cell Extract

✔️ Lactic Acid

✔️ Regenerative Skin Support

✔️ Cellular Energy Support

✔️ Collagen + Elastin Support

✔️ Barrier Repair

✔️ Intensive Overnight Hydration

✔️ Clinically Tested

✔️ Dermatologist Approved

---

As one of Hydrinity's newest arrivals, CÉLTHERA™ Advanced Overnight Repair Cream represents an exciting evolution beyond the traditional nighttime moisturizer. Rather than focusing solely on hydration, it combines ExoEGF™ biomimetic exosome technology, Centella Secretomes, NAD+ Boost Technology, senolytic renewal technology, multiple ceramides, Supercharged HA™, and Ectoin to support the skin from several different angles while you sleep.

For clients focused on fine lines, wrinkles, firmness, elasticity, dehydration, barrier health, texture, radiance, resilience, and long-term skin quality, CÉLTHERA™ delivers a sophisticated regenerative approach to nighttime skincare. And paired with Hydrinity's new RetaXome™ Retinal Boost Treatment Pads, it creates an especially compelling renew + repair nighttime regimen designed to resurface the skin while simultaneously supporting recovery, hydration, and barrier strength.